• Users Online: 899
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2015  |  Volume : 40  |  Issue : 1  |  Page : 24-29

Value of thrombopoietin level and platelet size in patients with ischemic stroke


1 Department of Clinical and Chemical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
2 Department of Internal Medicine and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
3 Department of Neurology, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Correspondence Address:
Yasmin N El-Sakhawy
Department of Clinical and Chemical Pathology, Faculty of Medicine, Ain Shams University, Cairo
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-1067.155790

Rights and Permissions

Background Stroke is a disease that affects the blood vessels supplying the brain with interruption of blood flow and thus oxygen delivery to a certain area of the brain, with rapid loss of brain functions. It is the third most common cause of death worldwide, ranking behind heart diseases and all forms of cancers. Aim The aim of this study was to evaluate the mean platelet volume (MPV) and thrombopoietin (TPO) hormone concentration in patients with acute ischemic stroke and compare this with healthy controls. Patients and methods This study was carried out prospectively on 100 patients with acute ischemic stroke who fulfilled the inclusion criteria and compared with 50 control participants. All patients were recruited to the study within the first 24 h after stroke. MPV and TPO concentrations were measured on admission. Results A high TPO concentration was found in two-third of the patients, whereas no participant in the control group had a high TPO concentration. In addition, high MPV was found in about half of the patients. There was a statistically significant difference in the levels of both MPV and TPO between the patient and the control group, which implies increased megakaryopoiesis and increased platelet activity in acute ischemic stroke.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1240    
    Printed30    
    Emailed0    
    PDF Downloaded118    
    Comments [Add]    

Recommend this journal