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CASE REPORT
Year : 2019  |  Volume : 44  |  Issue : 3  |  Page : 193-194

A case of hemoglobin J-Meerut detected from Gujarat, India


Department of Anthropology, University of Delhi, Delhi, India

Correspondence Address:
Benrithung Murry
Department of Anthropology, University of Delhi, Delhi 110007
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ejh.ejh_13_19

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A 19-year-old man who participated in the thalassemia screening program was found to have a normal hematological parameter with a slightly elevated mean corpuscular hemoglobin concentration (MCHC) and RDW (CV). The high-performance liquid chromatography also shows normal hemoglobin (Hb) F and Hb A2, but falls within the α-thalassemia trait and became suspected in the presence of a Hb variant. Hb electrophoresis was performed and molecular characterization was done with Sanger sequencing, and then identified the variant as Hb J-Meerut. Proper identification of such variant Hb could avoid mismanagement of diabetic patients as it is earlier reported to show a falsely lower level of HbA1c than expected.


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