The Egyptian Journal of Haematology

CASE REPORT
Year
: 2018  |  Volume : 43  |  Issue : 2  |  Page : 94--95

Successful treatment with bortezomib and dexamethasone combination in a patient with monoclonal gammopathy of renal significance


Figen Atalay 
 Department of Hematology, School of Medicine, Baskent University, Istanbul, Turkey

Correspondence Address:
Figen Atalay
Oymaci sk. No. 7 Altunizade, Uskudar, 34000
Turkey

A 40-year-old woman was reported to the nephrology outpatient clinic because of sudden-onset hypertensive attack, massive proteinuria, and high levels of creatinine. She had no previous medical history. Membranoproliferative glomerulonephritis and monoclonal κ light chain staining was seen on renal biopsy. She was evaluated for plasma cell diseases in hematology clinic. She was diagnosed as having monoclonal gammopathy of renal significance. Six courses of bortezomib plus dexamethasone were given to her. After this treatment schedule, her renal dysfunction and hypertension were resolved. Monoclonal gammopathy of renal significance is a disease caused by monoclonal immunoglobulins secreted by clonal B cells. Monoclonal gammopathy of renal significance should be considered with any unexplained renal impairment or proteinuria. Hematology department must be consulted as well. If treatment is delayed, permanent kidney damage can occur.


How to cite this article:
Atalay F. Successful treatment with bortezomib and dexamethasone combination in a patient with monoclonal gammopathy of renal significance.Egypt J Haematol 2018;43:94-95


How to cite this URL:
Atalay F. Successful treatment with bortezomib and dexamethasone combination in a patient with monoclonal gammopathy of renal significance. Egypt J Haematol [serial online] 2018 [cited 2020 Aug 12 ];43:94-95
Available from: http://www.ehj.eg.net/article.asp?issn=1110-1067;year=2018;volume=43;issue=2;spage=94;epage=95;aulast=Atalay;type=0